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Observation

However in the subsequent longitudinal study, while motor learning was significantly slower in adults over 62 years old, motor memory was pristinely preserved in normal adults from 18 to 95 years old.

Mapping in APK: for APKID_14330 Age 18 - 95 years is linked via AgeOfObservation to , MOTOR MEMORY,, | "Memories that last in old age: motor skill learning and memory preservation." Neurobiol Aging 2005; [PMID: 15718047]


The idea that age-related reductions in network size are proactively managed by older people is explored by examining the interrelationships among chronological age, network composition, social support, and feelings of social embeddedness (FSE) in a representative sample of 156 community-dwelling and institutionalized adults ages 70-104 years.

Mapping in APK: for APKID_30931 Age 70 - 104 years is linked via AgeOfObservation to , INSTITUTIONALIZED, COMPOSITION,, | "Close emotional relationships in late life: further support for proactive aging in the social domain." Psychol Aging 1994; [PMID: 8054179]


To clarify the cause of the age-related decrease in the responsiveness to L-DOPA seen in parkinsonian patients, we studied age-related changes in the mRNA levels of dopamine receptors (D1, D2) and of G proteins (Gs, Gi, Go) in 22 control human brains aged 50-105 years.

Mapping in APK: for APKID_26275 Age 50 - 105 years is linked via AgeOfObservation to , GS,, DOPAMINE, MRNA, L-DOPA,, | "Age-related decrease in responsiveness to L-DOPA is not due to changes in dopamine receptor mRNAs or G protein mRNAs." J Neural Transm 1996; [PMID: 8739845]


Results (N=883, aged 65 to 98 years) revealed that (a) affection was relatively high and status was relatively low in all age and loss groups; behavioral confirmation showed negative age and loss effects but was better predicted by loss; (b) the three needs relate differentially to indicators of subjective well-being: affection and behavioral confirmation relate positively to life satisfaction; status and behavioral confirmation relate positively to positive affect and negatively to negative affect.

Mapping in APK: for APKID_13167 Age 65 - 98 years is linked via AgeOfObservation to , RELATE,, | "Which social needs are important for subjective well-being? What happens to them with aging?" Psychol Aging 2006; [PMID: 16768575]


METHODS: A cross-sectional study was carried out in 2 rural sites (Borobudur and Sumedang) and 1 urban site (Jakarta) among mainly Javanese and Sundanese elderly (n = 719, 52-98 years of age).

Mapping in APK: for APKID_9268 Age 52 - 98 years is linked via AgeOfObservation to , RURAL,, | "High tofu intake is associated with worse memory in elderly Indonesian men and women." Dement Geriatr Cogn Disord 2008; [PMID: 18583909]


Using an O2 consumption rate of 1 fmol/min/cell, which was not observed in any transformant among 158 derived from individuals 20 weeks (fetal) to 37 years of age, as a cut-off to identify respiratory-deficient clones, 11 such clones were found among 198 transformants derived from individuals 39-103 years of age.

Mapping in APK: for APKID_26224 Age 39 - 103 years is linked via AgeOfObservation to , FETAL,, O2,, | "Aging-dependent functional alterations of mitochondrial DNA (mtDNA) from human fibroblasts transferred into mtDNA-less cells." J Biol Chem 1996; [PMID: 8663253]


In a primary set of 24 subjects (age range 34-97 years) examined, microglial cells immunoreactive for ferritin were found to constitute a subpopulation of the larger microglial pool labeled with an antibody for HLA-DR antigens.

Mapping in APK: for APKID_8584 Age 34 - 97 years is linked via AgeOfObservation to , FERRITIN, ANTIBODY,, | "Microglial dystrophy in the aged and Alzheimers disease brain is associated with ferritin immunoreactivity." Glia 2008; [PMID: 18442088]


Age and functional health constraints were examined as predictors of individual differences and intraindividual change in subjective well-being, as indicated by positive and negative affect, using cross-sectional (N = 516) and longitudinal (N = 203) samples from the Berlin Aging Study (age range 70-103 years).

Mapping in APK: for APKID_22228 Age 70 - 103 years is linked via AgeOfObservation to , SUBJECTIVE WELL-BEING, WELL-BEING,, | "Is age-related stability of subjective well-being a paradox? Cross-sectional and longitudinal evidence from the Berlin Aging Study." Psychol Aging 2000; [PMID: 11014714]


To establish a difference of the relative contents (RCs) of elements among the cervical, thoracic, and lumbar intervertebral disks and its age-related change, the intervertebral disks between the axis and the sacrum, which were resected from the nine cadavers who died at 53 to 99 yr old, were analyzed by inductively coupled atomic plasma emission spectrometry.

Mapping in APK: for APKID_26106 Age 53 - 99 years is linked via AgeOfObservation to , DIED, CADAVERS, PLASMA,, ELEMENTS,, | "Difference of mineral contents in human intervertebral disks and its age-related change." Biol Trace Elem Res 1996; [PMID: 8773752]


An observational study was performed on a consecutive series of 1716 type 2 diabetic outpatients (age range: 28-96 years). After adjusting for age and sex, hazard ratios of MS for cardiovascular mortality were 1.17 (0.42-3.22) in patients >80 years old

Mapping in APK: for APKID_62 Age 80 - 96 years is linked via AgeOfObservation to NON-INSULIN-DEPENDENT DIABETES MELLITUS, CARDIOVASCULAR MORTALITY, DEATH, METABOLIC SYNDROME, | "Metabolic syndrome and cardiovascular mortality in older type 2 diabetic patients: a longitudinal study. " J Gerontol A Biol Sci Med Sci. 2008; [PMID: 18559642]


Finally, formyl-methionyl-leucyl-phenylanaline (FMLP)-triggered O2- release was reduced in all elderly groups, while depression of O2- production was seen in subjects between the age of 86 and 104 years using phorbol 12-myristate 13-acetate (PMA) as agonist.

Mapping in APK: for APKID_30920 Age 86 - 104 years is linked via AgeOfObservation to , DEPRESSION,, PHORBOL, PMA, AGONIST,, | "Age-associated changes of neutrophil responsiveness in a human healthy elderly population." Cytobios 1994; [PMID: 7774287]


The relation between the intake of antioxidant flavonoids and subsequent risk of cancer was studied among 9,959 Finnish men and women aged 15-99 years and initially cancer free.

Mapping in APK: for APKID_25452 Age 15 - 99 years is linked via AgeOfObservation to CANCER, FLAVONOIDS, ANTIOXIDANT,, | "Dietary flavonoids and the risk of lung cancer and other malignant neoplasms." Am J Epidemiol 1997; [PMID: 9247006]


The stiffness of the human cornea increases by a factor of approximately two between the ages of 20 and 100 years. This variation is relevant to the algorithms used to predict the response to incisional and ablative refractive surgery and will also impact on the formulae used to calculate intraocular pressure by applanation.

Mapping in APK: for APKID_4000 Age 20 - 100 years is linked via AgeOfObservation to , STIFFNESS, CORNEA,, | "Age-related differences in the elasticity of the human cornea." Invest Ophthalmol Vis Sci 2010; [PMID: 20847118]



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